Disposable, integrated and large-scale are the development trend of cell gene therapy production equipment and technology.

After the cells are inoculated or subcultured, the experimenter should make routine examination of the cells every day or at most 1 ~ 2 days. Observe the morphology and growth of cells, as well as the pH change of culture, whether there is pollution, etc. According to the dynamic changes of cells, do fluid replacement or passage treatment. If abnormal conditions are found, take measures in time.

Vaccine is an automatic immune agent for the prevention of infectious diseases, which is made of pathogenic microorganisms (such as bacteria, viruses, etc.) and their metabolites through artificial virus reduction, inactivation or genetic engineering. According to the different types of infectious disease pathogens it prevents, it can be roughly divided into bacterial vaccines and viral vaccines. Many viral vaccines used in the population now need to be prepared through the process of virus culture, purification, concentration, inactivation or lysis. Because virosomes are a kind of parasitic microorganisms specialized in host cells, their reproduction needs to be carried out in their specific host cells. Therefore, the cultivation of viruses in the production of viral vaccines requires the cultivation of animal cells in which the virosomes can reproduce first.

When it comes to vaccines, there are many kinds, including: virus vaccines, protein based vaccines, viral vector vaccines, nucleic acid vaccines - what kind of vaccines are they? What are the advantages and disadvantages?

Experts believe that automation and informatization are the only way to ensure the quality of drugs. If this is not well understood in the industry, it is relatively difficult to promote this aspect. In terms of automation, the production process of the pharmaceutical industry can not simply apply automation, which can change some problems, especially in pharmaceutical equipment.

01 introduction to biopharmaceutical Biopharmaceutical is a product for prevention, treatment and diagnosis that uses biotechnology to separate effective components from organisms, biological tissues, cells and body fluids. Biopharmaceutical is an interdisciplinary comprehensive field formed by the combination of biotechnology and the pharmaceutical industry, covering chemical pharmaceuticals, biotechnology drugs, traditional Chinese medicine, medical devices and health industries. It is one of the most active fields in the current international scientific frontier. Biopharmaceutical raw materials are mainly natural biological materials, so the safety is relatively high and the side effects are relatively small. These significant advantages make biopharmaceutical accepted by more and more people, and it is also one of the reasons for the rapid development of biopharmaceutical. At present, biopharmaceutical is the industry with the most extensive application of biotechnology, and is also considered to be one of the most promising industries in the 21st century. Biopharmaceutical products include antibodies, vaccines, blood products, cell therapy, recombinant proteins, diagnostic reagents, etc., which are mainly used for the treatment of tumors, AIDS, cardiovascular and cerebrovascular diseases, hepatitis, autoimmune diseases and metabolic related diseases.