Benefits of biopharmaceutical

Benefits of biopharmaceutical

26-07-2022

Benefits of biopharmaceutical

 

Biological agents are not only different from general drugs in raw materials, but also in production processes. In short, it uses modern biotechnology to produce drugs with the help of some microorganisms, plants or animals. Protein or nucleic acid drugs developed by DNA recombination technology or other new biological technologies also become biological agents. Pure biological agents, that is to say, they do not contain traditional chemical drugs except excipients.

 

The earliest biological agent was insulin in 1982. At present, there are only about 50 kinds of biological agents approved for marketing at home and abroad, and there are hundreds of kinds of very hot disciplines under research. The difference and benefit from other drugs is. In the study of pathology and pathophysiology, it is found that proteins or peptides in the body are unbalanced in the process of many diseases, so proteins and peptides have been paid attention to in maintaining the balance of the body and treating diseases. Traditional chemical drugs treat diseases by regulating protein synthesis or the secretion of some hormones and cytokines on the basis of small molecules. Biological agents directly supplement the required proteins, hormones, cytokines, etc. However, this kind of drug is very unstable. How to maintain its production, transportation, storage and stability in the human body is the focus of research.

 

As we all know, proteins and peptides have very large molecular weight and are digested by enzymes. Therefore, at present, most biological agents cannot be made into oral preparations. They usually lose their activity by enzyme metabolism in the mouth and gastrointestinal tract. Even if they survive, they cannot be absorbed by the gastrointestinal tract due to their large molecular weight. Therefore, the most commonly used is still injections. At present, dosage forms absorbed through nasal mucosa and rectum have also been developed. Octreotide is now a common biological agent, which is taken orally.

 

In general, the advantage of biological agents is that the treatment is direct, what disorders can be filled, and how many deficiencies can be filled, which is more direct than chemical drugs and more personalized than chemical drugs. The disadvantage is that it is very unstable and not easy to absorb. It is not as easy to take as chemical drugs.

 

The cfam series cell factory automation equipment of Shenyang GREAT ELITES Intelligent Equipment Co., Ltd. is mainly used in biopharmaceutical cell multiplication culture, which can realize the automatic functions of infusion, liquid level leveling, drainage, cell digestion and vibration in the cell culture process. The equipment is suitable for the production enterprises that produce a large number of vaccines and stem cells.


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